Insulin resistance (IR) with resultant hyperinsulinism is basically the origin of the development process from obesity to insulin-independent diabetes mellitus (NIDDM). This process contributes to a reduced physical activity that is manifested in a reduced physical ability. Under the influence of a regular individually measured physical activity of aerobic character, it is possible to increase biological efficiency of insulin and affect the process of early and evolutive atherosclerosis. Finding a more effective program of physical activity for preventing these processes is the goal of their preventive and therapeutic application.