Efects of altitude to blood parameters

Reducing of partial pressure of oxygen in the air leads to a reduced arterial oxygen saturation and increases secretion of erythropoietin, wich stimulates erythropoiesis.

Study included 63 healthy children aged 7 years,devided into 3 groups. I group consists of 21 children from suburb of altitude of 370 m, II group of 22 children from the village on 822 m, III group of 21 children from the town on 411 m. Complete blood count was determined on a Hematology analyzer HmX ( Beckman Coulter).

Statistical analysis of data showed that children from II group have a higher average values of erythrocytes than children from the I (p<0.01) and III (p < 0.05),and the higher values of hemoglobin than children from I and III ( p<0.01). II and III group had lover average values of leukocytes,related to I group (p <0.01).

The boys from II group had more erythrocytes and hemoglobin then boys from I ( p<0.01), and more platelets than boys from the III group (p<0,05), but less leukocytes than boys from I and III group (p < 0.01). Girls from II group had higher values of erythrocytes, hemoglobin, hematocrit and platelets ( p<0.01) than the girls from I group.It is not found statistically significant variation of parameters between boys and girls within the same group nor erythrocytes and hemoglobin of I and II and platelets of all groups (p>0.05).

Results show that stay in the village is usefull for stimulation of erythropoiesis.

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